Culture, dining and nightlife are just a few of the reasons to find yourself in sunny Brisbane. This sprawling, constantly-evolving river city is for the young and the young at heart. Shop at the outdoor markets, where you'll find fashion, crafts and produce. Beaches are the order of the day here, too, with North Stradbroke Island and Moreton Island attracting hordes of sunbathers.

About halfway down the Oregon coast, the picturesque Yaquina Head Lighthouse welcomes you to Newport, a town known for its Dungeness crab and glorious harbor under the graceful Yaquina Bay Bridge. The historic Bayfront offers a mixture of shops, galleries, canneries and restaurants that serve fresh clam chowder, shrimp, oysters, crab and salmon.

French Guiana, tucked between Brazil and Suriname on the northeast coast of South America, offers an unexpected blend of Amazonian wilderness, colonial intrigue, and French flair. As an overseas department of France, it uses the euro, speaks French, and has croissants alongside cassava bread at breakfast. Yet just beyond the cafés of Cayenne, vast rainforest stretches for hundreds of kilometers, home to rare wildlife, remote rivers, and Indigenous communities.

Originating as a tiny fishing village in 1038, modern Kehl has become an important link between Germany and France. Rhine River cruises most often use Kehl as their gateway to the much larger and better-known Strasbourg. The savvy traveler, though, might choose to skip the jaunt across the river and enjoy many similar sights, shopping and cuisine as those offered in the teeming French city.

Nestled in the Aburrá Valley and surrounded by the Andes mountains, Medellín offers a stunning backdrop for visitors and boasts a pleasant climate year-round, earning it the nickname "City of Eternal Spring."